T cell migration, search strategies and mechanisms
2016年2月8日 · T cell migration is essential for T cell responses; it allows for the detection of cognate antigen at the surface of antigen-presenting cells and for interactions with other cells …
The spatio-temporal control of effector T cell migration
2021年2月24日 · Understanding spatio-temporal regulation of T cell migration will lead to novel therapies aimed at inhibiting the dysregulated autoimmune and allergic conditions as well as …
T-Cell Function and Migration — Two Sides of the Same Coin
2000年10月5日 · What are the consequences of pathologically inefficient, excessive, or misguided migration of T cells? How can we exploit this knowledge for therapeutic or diagnostic purposes?
T cell migration, search strategies and mechanisms - PubMed
T cell migration is essential for T cell responses; it allows for the detection of cognate antigen at the surface of antigen-presenting cells and for interactions with other cells involved in the …
T cell migration requires ion and water influx to regulate actin ...
2023年12月6日 · Migration of T cells is essential for their ability to mount immune responses. Chemokine-induced T cell migration requires WNK1, a kinase that regulates ion influx into the …
The integration of T cell migration, differentiation and function
2013年4月19日 · Effector T cells use various strategies to increase the efficiency of their scanning for antigen in non-lymphoid tissues. These strategies include the use of Lévy walks and …
The spatiotemporal control of effector T cell migration
Understanding spatiotemporal regulation of T cell migration will lead to novel therapies aimed at inhibiting the dysregulated autoimmune and allergic conditions as well as augmenting the host …
T Cell Trafficking through Lymphatic Vessels - Frontiers
2016年12月20日 · T cell migration within and between peripheral tissues and secondary lymphoid organs is essential for proper functioning of adaptive immunity. While active T cell migration …
The spatio-temporal control of effector T cell migration
Recent advances in real-time in situ imaging of effector T cell migratory behaviour have revealed a great degree of mechanistic plasticity that enables effector T cells to push and squeeze their …
Thymic Emigration: When and How T Cells Leave Home1
2008年8月15日 · Thus, to date the thymus is known to export at least six different populations of T cells: γ/δ T cells, naive CD4 and CD8 α/β T cells, NKT cells, T reg cells, and IEL or IEL …