ROS and ROS-Mediated Cellular Signaling - PubMed
In this review paper, we particularly focus on the pattern of the generation and homeostasis of intracellular ROS, the mechanisms and targets of ROS impacting on cell-signaling proteins (NF-κB, MAPKs, Keap1-Nrf2-ARE, and PI3K-Akt), ion channels and transporters (Ca (2+) and mPTP), and modifying protein kinase and Ubiquitination/Proteasome System.
Photosynthetic ROS and retrograde signaling pathways
2024年9月17日 · Intricate molecular events underlying reactive oxygen species (ROS)-triggered chloroplast-to-nucleus retrograde signaling. Reactive oxygen species are produced in chloroplasts not only during photosynthesis (as shown in Fig. 1) but also during tetrapyrrole biosynthesis (TBS
TXNDC9 regulates oxidative stress-induced androgen receptor signaling ...
2019年9月2日 · Here, we report that the thioredoxin domain-containing 9 (TXNDC9) is an important regulator of ROS to trigger AR signaling. TXNDC9 expression is upregulated by ROS inducer, and increased...
ROS as signalling molecules: mechanisms that generate ... - Nature
Reactive oxygen species (ROS) have been shown to be toxic but also function as signalling molecules. This biological paradox underlies mechanisms that are important for the...
Androgen receptor signaling–mitochondrial DNA–oxidative …
2022年8月31日 · Both AR signaling and mtDNA affect apoptosis, metabolism regulation, cellular calcium storage and homeostasis, intracellular calcium signaling, and redox homeostasis. In this review, we will attempt to understand how the crosstalk between AR-mtDNA-OXPHOS is responsible for “life or death” decisions inside the cells.
TXNDC9 regulates oxidative stress-induced androgen receptor signaling …
Here, we report that the thioredoxin domain-containing 9 (TXNDC9) is an important regulator of ROS to trigger AR signaling. TXNDC9 expression is upregulated by ROS inducer, and increased TXNDC9 expression in patient tumors is associated with advanced clinical stages.
Reactive oxygen species and cell signaling. Review
2024年2月1日 · Reactive oxygen species (ROS) activate JNK, p38 and ERK mitogen-activated protein kinases (MAPK), which upregulate c-Jun and c-Fos expression at the transcriptional level. Expression of c-Jun, a target gene of Jun/AP-1, increases through JNK-induced transactivation.
Isoproterenol induces MD2 activation by β-AR-cAMP-PKA-ROS
2023年11月2日 · We demonstrated that ISO induced MD2 activation in cardiomyocytes via β1-AR-cAMP-PKA-ROS signalling axis, and induced inflammatory responses in macrophages via β2-AR-cAMP-PKA-ROS axis. This...
ROS and ROS-Mediated Cellular Signaling - Wiley Online Library
2016年2月22日 · In this review paper, we particularly focus on the pattern of the generation and homeostasis of intracellular ROS, the mechanisms and targets of ROS impacting on cell-signaling proteins (NF- κ B, MAPKs, Keap1-Nrf2-ARE, and PI3K-Akt), ion channels and transporters (Ca 2+ and mPTP), and modifying protein kinase and Ubiquitination/Proteasome System.
Oxidative stress, consequences and ROS mediated cellular signaling …
2018年2月1日 · ROS act as an intracellular signaling component and is associated with various inflammatory responses, chronic arthropathies, including rheumatoid arthritis (RA). It is well documented that ROS can activate different signaling pathways having a vital importance in the patho-physiology of RA.
- 某些结果已被删除