RNA interference - Wikipedia
RNA interference (RNAi) is a biological process in which RNA molecules are involved in sequence-specific suppression of gene expression by double-stranded RNA, through translational or transcriptional repression.
RNA Interference (RNAi) - National Center for Biotechnology Information
2017年11月9日 · RNA interference or Post-Transcriptional Gene Silencing is a conserved biological response to double-stranded RNA that mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and …
RNA Interference: Biology, Mechanism, and Applications - PMC
Double-stranded RNA-mediated interference (RNAi) is a simple and rapid method of silencing gene expression in a range of organisms. The silencing of a gene is a consequence of degradation of RNA into short RNAs that activate ribonucleases to target homologous mRNA.
RNA interference | Explanation, Function, & Examples | Britannica
2024年10月18日 · RNA interference (RNAi), regulatory system occurring within eukaryotic cells (cells with a clearly defined nucleus) that controls the activity of genes. RNAi functions specifically to silence, or deactivate, genes.
Molecular mechanisms of RNA interference - PMC - PubMed …
The discovery of RNA interference (RNAi) revolutionized our understanding of gene regulation by revealing an array of related pathways in which small ~20–30 nucleotide (nt) non-coding RNAs and their associated proteins control the expression of genetic information .
RNA Interference Technology - PMC
RNA interference (RNAi) is the biological process of mRNA degradation induced by complementary sequences double-stranded (ds) small interfering RNAs (siRNA) and suppression of target gene expression.
Revealing the world of RNA interference | Nature
2004年9月15日 · The recent discoveries of RNA interference and related RNA silencing pathways have revolutionized our understanding of gene regulation.
RNA interference in biology and disease - PMC - National Center …
2005年8月1日 · RNA interference (RNAi) is a conserved biologic response to double-stranded RNA that results in the sequence-specific silencing of target gene expression.
From guide to target: molecular insights into eukaryotic RNA ...
2015年1月7日 · RNA interference (RNAi) is a process by which small noncoding RNAs direct molecular machinery to silence gene expression. In this Review, Ipsaro and Joshua-Tor discuss the mechanisms and ...
RNA interference in the era of nucleic acid therapeutics
2024年2月26日 · Two decades of research on RNA interference (RNAi) have transformed a breakthrough discovery in biology into a robust platform for a new class of medicines that modulate mRNA expression.