Major side effects of class I antiarrhythmic drugs - UpToDate
2023年12月1日 · Quinidine, disopyramide, procainamide, lidocaine, mexiletine, flecainide, and propafenone are all class I antiarrhythmic drugs (table 1) used for the treatment of various atrial and ventricular arrhythmias. This topic will review the major side effects of the various drugs.
Procainamide - StatPearls - NCBI Bookshelf
2023年5月8日 · Researchers have also studied the utility of procainamide compared to lidocaine in terminating sustained ventricular tachycardia in patients with structural heart defects. In this retrospective study from Circulation Journal, procainamide was found to be more effective than lidocaine in the termination of the arrhythmia.
Antiarrhythmic Medications - StatPearls - NCBI Bookshelf
2024年2月28日 · Procainamide is recommended to restore sinus rhythm in patients with Wolff-Parkinson-White (WPW) syndrome, in whom atrial fibrillation (AF) occurs without hemodynamic instability associated with a wide QRS complex or a rapid pre-excited ventricular response. Procainamide also can be useful in terminating ventricular tachycardia and arrhythmia.
Comparison of procainamide and lidocaine in terminating …
1996年7月1日 · Efficacy of procainamide and lidocaine in terminating spontaneous monomorphic ventricular tachycardia (VT) was assessed in a randomized parallel study. Patients with acute myocardial infarction and those with poor hemodynamic tolerance of VT were excluded.
Drug Interactions Affecting Antiarrhythmic Drug Use
2022年5月2日 · Amiodarone, quinidine, and dofetilide are AADs with numerous and clinically significant drug interactions. Recent studies have also demonstrated increased morbidity and mortality with the use of digoxin and other AAD which interact with P-gp.
Procainamide: Uses, Interactions, Mechanism of Action
Procainamide is an agent indicated for production of local or regional anesthesia and in the treatment of ventricular tachycardia occurring during cardiac manipulation, such as surgery or catheterization, or which may occur during acute myocardial infarction, digitalis toxicity, or other cardiac diseases.
Pharmacologic Management for Ventricular Arrhythmias: …
2022年6月6日 · Ventricular arrhythmias (Vas) are a life-threatening condition and preventable cause of sudden cardiac death (SCD). With the increased utilization of implantable cardiac defibrillators (ICD), the focus of VA management has shifted toward reduction of morbidity from VAs and ICD therapies.
The Pharmacology and Clinical Use of Lidocaine and Procainamide
Both procainamide and lidocaine are useful for acutely treating cardiac arrhythmias, and procainamide can be useful in chronic antiarrhythmic regimens.
Procainamide Monograph for Professionals - Drugs.com
2024年10月25日 · Reduce dosage in renal insufficiency and/or CHF and in critically ill patients; determine plasma concentrations of procainamide and its major metabolite (N-acetyl procainamide) and adjust dosage to maintain desired concentrations.
Procainamide: Indications, Side Effects, Warnings - Drugs.com
2024年3月23日 · Uses of Procainamide: It is used to treat certain types of abnormal heartbeats. This medicine will be started in a hospital where you will be closely watched. Talk with your doctor. What do I need to tell my doctor BEFORE I take Procainamide? If you have an allergy to procainamide or any other part of procainamide.