The synthetic cathinones, butylone and pentylone, are …
Our data demonstrate that increasing the α-carbon chain length of methylone creates “hybrid” transporter compounds which act as DAT blockers but SERT substrates. Nevertheless, butylone and pentylone elevate extracellular dopamine and stimulate motor activity, suggesting both drugs possess significant risk for abuse.
N-Isopropyl Butylone - cfsre.org
Description: N-Isopropyl butylone is a novel synthetic stimulant and substituted cathinone bearing structural similarity to other beta-keto methylenedioxyamphetamines (noted by the suffix “-ylone”).
Methylone - Wikipedia
Methylone, also known as 3,4-methylenedioxy-N-methylcathinone (MDMC), is an empathogen and stimulant psychoactive drug. It is a member of the amphetamine, cathinone and methylenedioxyphenethylamine classes. Methylone is a slight modification of 3,4-methylenedioxymethamphetamine (MDMA, also known as ecstasy).
The synthetic cathinones, butylone and pentylone, are ... - PubMed
Our data demonstrate that increasing the α-carbon chain length of methylone creates "hybrid" transporter compounds which act as DAT blockers but SERT substrates. Nevertheless, butylone and pentylone elevate extracellular dopamine and stimulate motor activity, suggesting both drugs possess significan …
Comparative neuropharmacology of three psychostimulant …
Butylone particularly induces intense hyperlocomotion through an activation of 5-HT 2A receptors and an increase in extra-cellular dopamine concentration. The activation of 5-HT 1B receptors also contributes to this psychostimulant effect. This cathinone inhibits 5-HT and dopamine uptake as a consequence of a competition with the substrate.
Eutylone - Wikipedia
Eutylone (also known as β-keto-1,3-benzodioxolyl-N-ethylbutanamine, bk-EBDB, and N-ethylbutylone) is a stimulant and empathogenic drug of the phenethylamine, amphetamine, phenylisobutylamine, and cathinone families which was developed in the 1960s, [3][4] which is classified as a designer drug. [5] .
Butylone - Wikipedia
Butylone, also known as β-keto-N-methylbenzodioxolylbutanamine (βk-MBDB), is an entactogen, psychedelic, and stimulant psychoactive drug of the phenethylamine, amphetamine, phenylisobutylamine, and cathinone families.
A review of synthetic cathinones emerging in recent years …
We have identified 29 synthetic cathinones that have been detected for the first time from early 2019 to mid-2022. We described their structures, known intoxication symptoms, detected concentrations in biological material in poisoning cases, as well as the countries and dates of their first appearance.
Butylone - an overview | ScienceDirect Topics
Butylone, ethylone, mephedrone, and methylone cause serotonin release. Cathinone, methcathinone, and flephedrone act in a manner similar to amphetamines, preferentially causing the release of dopamine and inhibiting dopamine and …
Eutylone: Chemistry and Stimulant Properties of a …
Eutylone, also known as bk-EBDB or n-ethylbutylone, represents a stimulant within the synthetic cathinone family, categorized under the broader class of New Psychoactive Substances (NPS), often termed designer drugs, novel designer drugs, or bath salts.