Lipid Metabolism in Regulation of Macrophage Functions - Cell …
2020年10月6日 · In this review, we describe different aspects of how cellular lipid metabolism influences macrophage biology. More specifically, we discuss how lipids provide an important …
Reprogramming cholesterol metabolism in macrophages and its …
2022年1月11日 · Macrophages rapidly reprogram their metabolic state to facilitate inflammation, resolution, and effector functions [4, 5]. The metabolic reprogramming of macrophages targets …
Metabolism of tissue macrophages in homeostasis and pathology …
2021年12月7日 · In short, tissue fuels (such as glucose, lipids or amino acids) are converted into metabolites (such as pyruvate, tricarboxylic acid [TCA] cycle intermediates, fatty acids or free …
Current Understanding on the Role of Lipids in Macrophages and ...
This review discusses the significance of lipids in adipose tissue macrophages, tumor-associated macrophages, microglia and peritoneal macrophages. Accumulation of macrophages with …
Impact of Lipid Metabolism on Macrophage Polarization
2023年7月27日 · This review focuses on lipid metabolism and macrophage functions and addresses potential molecular targets for the treatment of macrophage-related diseases. While …
Macrophages and lipid metabolism - PMC - PubMed Central …
As it is now appreciated that cell metabolism not only provides energy but also greatly influences the phenotype and function of the cell, here we review how lipid metabolism affects …
Lipid Metabolism in Regulation of Macrophage Functions
2020年12月1日 · In this review, we describe different aspects of how cellular lipid metabolism influences macrophage biology. More specifically, we discuss how lipids provide an important …
Protumoral lipid droplet–loaded macrophages are enriched in …
2024年10月30日 · Here, we characterized tumor-associated foam cells (TAFs), a type of lipid droplet–loaded macrophage, ... Glioblastoma presents a formidable clinical challenge because …
Impact of Lipid Metabolism on Macrophage Polarization ... - MDPI
2023年6月28日 · Lipids and their metabolites are players in intricate signaling pathways that modulate macrophages’ responses to pathogens, phagocytosis, ferroptosis, and inflammation. …
Lipid Metabolism in Regulation of Macrophage Functions
Here, we review how macrophage lipid metabolism can be dynamically altered in different physiological and pathophysiological contexts and the key regulators involved. We also …