An atlas of healthy and injured cell states and niches in the human kidney
Jul 19, 2023 · We define niches for healthy and altered states across different regions of the human kidney spanning the cortex to the papillary tip, and identify gene expression and …
An atlas of healthy and injured cell states and niches in the human kidney
Understanding kidney disease relies on defining the complexity of cell types and states, their associated molecular profiles and interactions within tissue neighbourhoods 1. Here we …
New atlas of human kidney cells to help unlock kidney disease …
Jul 19, 2023 · Data from the Kidney Tissue Atlas will allow the comparison of healthy kidney cells to those injured by kidney disease, helping investigators understand the factors that contribute …
Kidney Tissue Atlas
The Kidney Tissue Atlas is a set of interactive tools built to promote retrieval, exploration, discovery, and analysis of the KPMP data by the greater research community. Learn more …
Detailed “kidney atlas” characterizes cells of the healthy adult kidney
This atlas delineates the biology of individual cells in various parts of the nephron and its surrounding tissue, demonstrating how they are defined not only by their position in the kidney, …
A reference tissue atlas for the human kidney | Science Advances
Jun 8, 2022 · Kidney Precision Medicine Project (KPMP) is building a spatially specified human kidney tissue atlas in health and disease with single-cell resolution. Here, we describe the …
Kidney Histology, Kidney Function, and Age - American Journal of Kidney …
Jan 13, 2021 · In summary, the study by Li et al represents an important contribution to the literature, as the findings highlight the relationship between kidney histology, kidney function, …
Single-cell profiling of healthy human kidney reveals features of …
Dec 10, 2022 · We provide a map of healthy human kidney using single-cell RNA sequencing (scRNAseq) of 19 living donors, capturing parenchymal and immune cell transcriptomes …
Single-cell multi-omic and spatial profiling of human kidneys ...
Jul 24, 2024 · Here we present the spatial molecular principles of kidney health and disease by generating a comprehensive and spatially resolved human kidney atlas and combining single …
The kidney—more than the sum of its cellular parts
Aug 30, 2022 · The Kidney Tissue Atlas is accessible via https://atlas.kpmp.org/ and currently holds data from scRNA-seq as well as spatial transcriptomics of healthy kidney tissue and …