Rapid Crystal Dissolution in Gout - Medscape
For example, most patients (90%) with <10 years duration of gout but few patients (25%) with >10 years gout duration, were free of crystals by 12 months (median serum urate levels while on …
Gout: Diagnosis and Management in Primary Care - Medscape
2024年12月12日 · Hyperuricemia is the most important risk factor for gout and leads to deposition of monosodium urate crystals in various tissues and joints, leading to inflammation and …
Dual-energy CT: A New Diagnostic Tool for Gout - Medscape
Uric acid crystals were identified in synovial fluid in 12 patients, and CT was positive in all of them (100% sensitivity). In the 19 patients whose fluid was negative for uric acid crystals, CT ...
Treat Gout to Target Based on Uric Acid Level, Not Symptoms
2024年6月18日 · Basing the treatment of gout on reaching and maintaining target serum uric acid level is already endorsed in guidelines, but a randomized trial finally showed the advantage …
IL-6 Receptor Inhibitors Show Early Promise for CPPD - Medscape
2024年12月20日 · Both the monosodium urate (MSU) crystals associated with gout and CPP crystals induce inflammation dependent on IL-1 beta, but IL-1 beta inhibitors have been …
New Gout Drugs Might Increase Patients at Target Urate Level
2024年7月9日 · Patients with refractory gout, defined as failure to normalize sUA or control symptoms with a xanthine oxidase inhibitor, were randomly assigned to receive 0.15 mg SEL …
Target These Serum Urate Levels to Prevent Gout Flares - Medscape
2024年2月6日 · In fact, "95% and 98% of gout flares can be potentially preventable at the population level if serum urate levels < 6 and < 5 mg/dL can be met, respectively, and 100% of …
Gut Microbiome Has Potential to Counter Gout - Medscape
2024年11月18日 · Efforts to combat hyperuricemia may find help from gut microbes, according to Dylan Dodd, MD, PhD, who spoke at the annual research symposium of the Gout, …
Optimized Hospital Care Improves Gout Treatment Uptake
2024年4月29日 · "The number of new cases of gout dropped by about one third in the first year of the pandemic," Russell said. Incidence declined from 1.78 to 1.23 per 1000 adults.
Another Benefit of Gout Treatment: CV Risk Reduction - Medscape
2024年5月16日 · NEW YORK CITY — Urate, the culprit of gout, affects the vasculature in multiple ways that can raise cardiovascular risk (CV) in an individual with gout, and following guidelines …