NexGard® COMBO Broad-Spectrum Parasiticide for Cats
NexGard® COMBO (esafoxolaner, eprinomectin, and praziquantel topical solution) is the first and only broad-spectrum parasiticide for felines that protects against fleas and ticks, prevents heartworm disease, and treats and controls roundworms, hookworms, and tapeworms.
NexGard® Combo (esafoxolaner, eprinomectin, praziquantel), a …
The following articles in this special edition present the development studies regarding a new topical endectoparasiticide for cats containing three active substances: esafoxolaner (syn. (S)-afoxolaner), eprinomectin and praziquantel for cats with, or at risk of, mixed parasitic infestations with ectoparasites (fleas, ticks, and/or mites ...
AFOXOLANER - NEXGARD - for veterinary use on DOGS against …
2022年6月22日 · Afoxolaner is a broad-spectrum antiparasitic active ingredient used in veterinary medicine in pets against external parasites (fleas, ticks, lice, mites, etc.). It is not used against agricultural and household pests. It belongs to the chemical class of the isoxazolines.
DailyMed - NEXGARD COMBO- esafoxolaner, eprinomectin, and …
2024年9月27日 · NexGard® COMBO is a topical solution containing esafoxolaner, eprinomectin and praziquantel available in 0.3 mL and 0.9 mL unit applicators to treat cats from 1.8 lbs to 33 lbs. Each mL of NexGard® COMBO contains 12 mg of esafoxolaner, 4 mg of eprinomectin, and 83 mg of praziquantel.
Esafoxolaner/eprinomectin/praziquantel - Wikipedia
Esafoxolaner/eprinomectin/praziquantel, sold under the brand name Nexgard Combo, is a fixed-dose combination medication used for the treatment and control of flea infestations, ticks, ear mites, and infections caused by tapeworms and Toxocara cati in cats.
Pharmacokinetics of a novel endectoparasiticide topical …
Esafoxolaner, a purified enantiomer of afoxolaner with insecticidal and acaricidal properties, is combined with eprinomectin and praziquantel in NexGard ® Combo, a novel topical endectoparasiticide formulation for cats.
Boehringer Ingelheim Introduces NexGard® COMBO (esafoxolaner ...
2023年4月24日 · Each application of NexGard® COMBO contains esafoxolaner (12 mg per mL), which was specially formulated for cats to kill fleas and ticks. NexGard® COMBO also contains eprinomectin (4 mg per mL) to prevent heartworm disease and treat and control roundworms and hookworms, and praziquantel (83 mg per mL) for the treatment and control of tapeworms.
Efficacy of a novel topical combination of esafoxolaner, …
Esafoxolaner, a purified enantiomer of afoxolaner with insecticidal and acaricidal properties, is combined with eprinomectin and praziquantel, nematodicidal and cestodicidal compounds, in NexGard ® Combo, a novel topical endectoparasiticide formulation for cats.
Esafoxolaner is a member of the isoxazoline family, shown to bind at a site to inhibit insect and acarine ligand-gated chloride channels, in particular those gated by the neurotransmitter gamma-aminobutyric acid (GABA), thereby blocking pre- and post-synaptic transfer of chloride ions across cell membranes.
Boehringer Ingelheim Introduces NexGard® COMBO (esafoxolaner ...
2023年4月24日 · Each application of NexGard® COMBO contains esafoxolaner (12 mg per mL), which was specially formulated for cats to kill fleas and ticks. NexGard® COMBO also contains eprinomectin (4 mg per mL)...