Acetylcholine as a neuromodulator: cholinergic signaling shapes …
Here we identify actions of cholinergic signaling on cellular and synaptic properties of neurons in several brain areas and discuss the consequences of this signaling on behaviors related to …
Cholinergic System and Its Therapeutic Importance in …
GTS-21 inhibits Akt and NF-κB signaling pathway, thereby reducing the LPS-induced cytokine production in macrophages . It has recently been shown that GTS-21 ameliorates …
Basal forebrain cholinergic signalling: development ... - Nature
2023年2月23日 · The axons of the basal forebrain cholinergic neurons (BFCNs) that make up these different rostrocaudal pools take four distinct projection paths to innervate their targets: …
Distinct septo-hippocampal cholinergic projections separately
2024年11月8日 · We next investigated if stress-induced behavioral deficits could be rescued by targeting circuit-based cholinergic signaling pathways. Single-cell transcriptomics analysis of …
Physiology, Cholinergic Receptors - StatPearls - NCBI Bookshelf
Cholinergic receptors function in signal transduction of the somatic and autonomic nervous systems. The receptors are named because they become activated by the ligand …
Cholinergic receptor pathways involved in apoptosis, cell …
2009年8月27日 · Intriguingly, activation of diverse signaling molecules such as Ras-mitogen-activated protein kinase, phosphatidylinositol 3-kinase-Akt, protein kinase C and c-Src is …
Acetylcholine as a Neuromodulator: Cholinergic Signaling …
Acetylcholine changes the state of neuronal networks and modifies their response to internal and external inputs. Here, Picciotto et al. identify actions of cholinergic signaling on cellular and …
The relationship between cholinergic system brain structure …
2021年8月9日 · We assessed the structure–function relationship of the human cholinergic system and hypothesized that structural measures are associated with short-latency sensory afferent …
Cholinergic Signaling Dynamics and Cognitive Control of Attention
2020年5月24日 · Cholinergic signaling is elicited by presynaptic release of ACh that activates two classes of ACh receptors, nicotinic (nAChR) and muscarinic (mAChR), in a spatially and …
The cholinergic anti-inflammatory pathway in humans: State-of …
2022年5月1日 · Subsequent efferent vagal signaling can lead to downregulation of inflammatory cytokines (i.e., cholinergic anti-inflammatory pathway). This occurs in part through the release …