Pathology Outlines - Giant cell tumor of bone, NOS
The cortical bone is focally destroyed and replaced by a reactive rim of woven bone at the tumor periphery. Immunohistochemical stains for H3.3 G34W and p63 are positive in mononuclear cells. Overall, the appearance on computed tomography and magnetic resonance scans, morphological features and immunohistochemical profile support the diagnosis ...
Pathology Outlines - Bone & joints
F-N: fibrodysplasia ossificans progressiva fibrosarcoma of bone fibrous dysplasia fracture ganglion cyst giant cell tumor of bone, malignant giant cell tumor of bone, NOS gout and gouty arthritis grossing, frozen section & features to report hemangioma high grade surface osteosarcoma histology-bone histology-joints implant related changes ...
Pathology Outlines - Bacterial osteomyelitis (acute)
2022年7月18日 · The bone trabeculae have irregular contours and are fragmented They may be fractured and completely necrotic (so called bone sequester) There are intramedullary granulocyte infiltrates and fibrin exudates In bone tissue with a haemopoietic function (e.g. axial skeleton) there is a reduced or complete lack of haemopoiesis. Soft tissue changes:
Pathology Outlines - Osteoma, NOS
2021年8月3日 · Typically a solitary lesion (Nielson: Diagnostic Pathology - Bone, 2nd Edition, 2017, Surg Pathol Clin 2012;5:101) Tan-white Oval, round or polypoid Firm Well circumscribed and attached to the underlying bone Cut surface with dense compact bone or trabecular bone
Simple bone cyst - Pathology Outlines
2020年8月4日 · 12 year old girl with simple bone cyst of iliac bone (Hip Pelvis 2014;26:202) 20 year old man with simple bone cyst of calcaneum (Rom J Morphol Embryol 2017;58:689) 25 year old man with simple bone cyst of distal radius (BMC Musculoskelet Disord 2014;15:202) 26 year old man with simple bone cyst of humerus (World J Surg Oncol 2017;15:102)
Bone formation and growth - Pathology Outlines
2012年1月1日 · Bone formation is an ongoing process that alters the size and shape of bone by partial resorption of preformed bone tissue and simultaneous deposition of new bone (modeling and remodeling) Modeling is a process in which bone achieve its proper shape Modeling is responsible for the circumferential growth of bone and expansion of marrow cavity
Pathology Outlines - Paget disease
2023年2月8日 · Late: increased bone density, cortical thickening with marked tunneling, increased prominence of trabeculae, increased microfractures, loss of distinction between cortex and medulla; may have sharp demarcation between normal and affected bone; may extend into soft tissue if florid disease
Pathology Outlines - Brown tumor
2021年12月14日 · Aneurysmal bone cyst affects young adults and shows large blood filled spaces with intervening septae containing fibroblasts and giant cells. Central giant cell granuloma produces radiolucent lesions in children and young women and shows osteoclast-like giant cells near hemorrhagic areas, cellular vascular and fibrous stroma and new bone ...
Pathology Outlines - Fracture
2024年1月9日 · Fractures may not heal due to improper immobilization, devascularization of bone fragments, persistent infection or interposition of soft tissue between ends of bone Case reports 14 year old boy with hyperplastic fracture callus of femur mimicking osteosarcoma ( Front Endocrinol (Lausanne) 2021:12:622674 )
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2020年7月8日 · A sheath of new bone surrounding the sequestrum (N Engl J Med 2007; 356:e7) Medullary bone / medullary cavity / marrow cavity: The medullary cavity (medulla, innermost part) of bone is the central cavity where red bone marrow or yellow bone marrow (adipose tissue) is stored; hence, the medullary cavity is also known as the marrow cavity