Assessment of global health risk of antibiotic resistance genes
2022年3月23日 · Antibiotic resistance genes (ARGs) have accelerated microbial threats to human health in the last decade. Many genes can confer resistance, but evaluating the relative health risks of ARGs is...
Antibiotic resistance genes in bacteria: Occurrence, spread, and ...
2021年10月14日 · The origin and molecular basis of bacterial resistance is the presence of antibiotic resistance genes (ARGs). Investigations on ARGs mostly focus on the environments in which antibiotics are frequently used, such as hospitals and farms.
Antibiotic resistance in the environment - Nature
2021年11月4日 · Conceptual illustration of how evolution leading to the emergence of a new antibiotic resistance gene (ARG; red) in pathogens can involve the environment and/or the human/domestic animal ...
National Database of Antibiotic Resistant Organisms (NDARO)
To increase standardization, NCBI has developed and maintains a curated database of AMR genes and makes them available both as raw data and with an interactive web interface. To make AMR-related data more widely available, NCBI is collecting genetic and …
Antibiotic Resistance Genes - an overview - ScienceDirect
Antibiotic resistance genes generally have little effect on the host cell's overall fitness. For example, many of these genes actually destroy the antibiotic and do not alter the target site.
Antibiotic resistance genes: A global change factor
2024年7月30日 · This invited commentary paper discusses the concept of elevated antibiotic resistance genes as a global change factor. Antibiotic resistance genes (ARGs) are a critical global issue impacting human health, animal health, and the environment.
Latent antibiotic resistance genes are abundant, diverse, and …
2023年3月8日 · Bacterial communities in humans, animals, and the external environment maintain a large collection of antibiotic resistance genes (ARGs). However, few of these ARGs are well-characterized and thus established in existing resistance gene databases.
Molecular mechanisms of antibiotic resistance revisited
2022年11月21日 · In this Review, we explore recent advances in understanding how resistance genes contribute to the biology of the host, new structural details of relevant molecular events underpinning...
Antibiotic Resistance - StatPearls - NCBI Bookshelf
2023年6月20日 · Dissemination of antibiotic resistance genes is an ecological and public health concern. Certain bacteria are able to neutralize an antibiotic by altering its component to render it ineffective.
Antibiotic resistance: A key microbial survival mechanism that ...
2024年6月12日 · All mechanisms of HGT allow for the transfer of resistance genes from different species, thereby propagating resistance through bacterial communities. While the exchange of resistance genes can be achieved through any of these mechanisms, conjugation is common for acquired resistance in the clinic.