RNAi Therapeutics | How RNA Interference Works - Alnylam …
RNAi therapeutics is an innovative new class of medicines based on RNA interference (RNAi)—a breakthrough discovery in understanding how genes are regulated naturally within cells. The …
Taking RNAi from interesting science to impactful new treatments
2024年5月13日 · Alnylam Pharmaceuticals is translating the promise of RNA interference (RNAi) research into a new class of powerful, gene-based therapies. In this rendering, the green …
RNA interference - Wikipedia
RNA interference (RNAi) is a biological process in which RNA molecules are involved in sequence-specific suppression of gene expression by double-stranded RNA, through …
RNA Interference (RNAi) - National Center for Biotechnology Information
2017年11月9日 · RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is a conserved biological response to double-stranded RNA that mediates resistance to both …
Alnylam® Pharmaceuticals
the leading rnai therapeutics company Alnylam’s pioneering science has yielded the critical breakthroughs and innovations that have made RNA interference (RNAi)-based medicines a …
FDA approves first-of-its kind targeted RNA-based therapy to …
FDA approves new drug for treatment of polyneuropathy caused by hereditary transthyretin-mediated amyloidosis (hATTR). This is the first FDA-approved treatment for this rare, …
RNAi therapeutics are disrupting disease - Nature
There are six approved RNAi therapeutics — including five discovered at Alnylam — for conditions ranging from a rare form of amyloidosis to hypercholesterolaemia.
How the RNAi therapeutic ‘operating system’ is rewriting ... - Nature
RNAi therapeutics are inspired by a mechanism that exists in all cells to regulate gene expression, using specially-designed small interfering RNA (siRNA) that is complementary to specific …
Insight Into the Prospects for RNAi Therapy of Cancer
2021年3月15日 · RNA interference (RNAi), also known as gene silencing, is a biological process that prevents gene expression in certain diseases such as cancer. It can be used to improve …
RNAi-Based Therapeutics and Novel RNA Bioengineering …
2023年1月1日 · RNA interference (RNAi) provides researchers with a versatile means to modulate target gene expression. The major forms of RNAi molecules, genome-derived …