Urothelial Carcinoma: Divergent Differentiation and Morphologic ...
(F) Poorly-differentiated urothelial carcinoma remains in the 2022 WHO classification to encompasses undifferentiated carcinoma with osteoclastic giant cells and any other tumors in which a substantial component of the neoplasm does not show a definitive line of differentiation.
Staging & Grade - Bladder Cancer | Johns Hopkins Pathology
If the cancerous tissue looks very different from healthy tissue, it is called "poorly differentiated" or a "high-grade tumor." Many urologic surgeons classify a tumor’s grade based on the chance that the cancer will recur or grow and spread, called progression. They often plan treatment based on the grade, using the following categories:
Invasive Urothelial Carcinoma: Subtypes and Divergent …
2022年9月12日 · Invasive urothelial carcinoma shows morphologic and molecular heterogeneity along with variability in patient outcome. It can exist in a pure or classical form or may have components of either subtype histology or divergent differentiation (Table 1).
Urothelial Carcinoma, Poorly Differentiated | SpringerLink
2019年12月9日 · The poorly differentiated component is usually associated with recognizable usual urothelial carcinoma such as in situ urothelial carcinoma, papillary urothelial carcinoma, or invasive urothelial carcinoma in various percentages.
Pathology Outlines - Invasive urothelial carcinoma
2021年5月13日 · 8020/3 - poorly differentiated urothelial carcinoma ICD-10: C67.9 - malignant neoplasm of bladder, unspecified
Outcomes of poorly differentiated and plasmacytoid variant …
The aim of this study is to assess the course and management of poorly differentiated bladder urothelial carcinoma (UC), including plasmacytoid UC (PUC), in our local area. Although bladder cancer is relatively common, PUC is a rare and aggressive subtype with a poor prognosis that is still poorly understood.
Urothelial carcinoma: variant histology, molecular subtyping, and ...
2021年1月1日 · The poorly differentiated variant is an extremely rare entity that is not well defined. Its spectrum includes tumours with various histological variants showing mixed morphologies. 1 Because of its rarity, its exact character remains unresolved.
Histological variants of urothelial carcinoma: diagnostic, …
2009年5月29日 · Small-cell carcinoma may be mistaken for malignant lymphoma, poorly differentiated urothelial carcinoma with scant cytoplasm and even inflammation in a crushed, cauterized, superficial or scant...
Invasive Poorly Differentiated Urothelial Carcinoma
Expression of Indoleamine 2,3-Dioxygenase Gene Is a Feature of Poorly Differentiated Non-muscle-invasive Urothelial Cell Bladder Carcinomas. Hudolin T, Mengus C, Coulot J, Kastelan Z, El-Saleh A, Spagnoli GC Anticancer Res 2017 Mar;37(3):1375-1380. doi: 10.21873/anticanres.11458.
Outcomes of poorly differentiated and plasmacytoid variant …
2021年8月27日 · Poorly differentiated UC is demonstrated to have a poor prognosis with a high mortality rate, particularly when PUC is present. Given the rarity of these variants, further studies are necessary to explore the impact of current treatment options.