Melanocytoma - Wikipedia
A melanocytoma is a rare pigmented tumor that has been described as a variant of the melanocytic nevus [1] and is derived from the neural crest. [2] The term "melanocytoma" was introduced by Limas and Tio in 1972.
New and evolving concepts of melanocytic nevi and …
2019年10月28日 · Melanocytomas occupy intermediate genetic stages between nevus and melanoma and likely have an increased risk of malignant transformation as compared to nevi. This review provides an...
Optic Disk Melanocytoma and Optical Coherence Tomography …
Melanocytoma is a rare benign pigmented neoplasm that may occur anywhere in the uvea. It often affects the optic nerve head, but may even involve the adjacent retina and choroid in some cases. It is believed to be a congenital and non-hereditary lesion.
The Evaluation and Management of Optic Disc Melanocytoma
2011年5月1日 · Melanocytoma of the optic disc is an ophthalmic tumor that arises from melanocytes and is a variant of the melanocytic nevus. This pigmented lesion occurs on the optic disc and often extends into the peripapillary retina and choroid.
Melanocytoma of the optic disk: A review - PMC - PubMed …
Melanocytoma is a deeply pigmented variant of melanocytic nevus that classically occurs in the optic disk, sometimes with contiguous involvement of the adjacent retina or choroid. Historically, this tumor was often confused with malignant melanoma both clinically and histopathologically.
Melanocytoma: nomenclature, pathogenesis, natural history …
A melanocytoma (magnocellular nevus) is a benign pigmented tumor that may arise wherever uveal melanocytes are present. The most commonly observed site is on or adjacent to the optic nerve head. In the past this tumor was frequently misdiagnosed as a malignant melanoma and many unnecessary enucleati …
Melanocytomas - SpringerLink
2021年7月11日 · Melanocytomas are benign heavily pigmented tumors that arise from uveal melanocytes and typically appear as dark brown to black pigmented masses observed on the surface of the optic disk, in the anterior uveal tract, or more rarely in the choroid. Occasionally, melanocytomas have been reported to occur in the sclera [1] or conjunctiva [2].
The WHO 2018 Classification of Cutaneous Melanocytic …
The “multidimensional” World Health Organization (WHO) classification 2018 of melanocytic tumors encompasses nine melanoma pathways (seven of which for cutaneous melanoma) according to a progression model in which morphologically intermediate melanocytic tumors are cosidered as simulators and/or precursors to melanoma.
Melanocytoma of the optic disk: A review - LWW
2019年11月5日 · Melanocytoma is a deeply pigmented variant of melanocytic nevus that classically occurs in the optic disk, sometimes with contiguous involvement of the adjacent retina or choroid. Historically, this tumor was often confused with malignant melanoma both clinically and histopathologically.
2023年7月19日 · We report the clinical and histologic presentation of 51 cutaneous melanocytic neoplasms with a PKC fusion gene (involving PRKCA in 35 cases, PRKCB in 15 cases, and PRKCG in a single case). Most tumors were in young adults (median age, 29.5 years; range,1-73 years) but some presented in newborns.