Vegfa/vegfr2 signaling is necessary for zebrafish islet vessel ...
2019年3月5日 · We also assessed the role of kdr and kdrl, the primary receptors of VegfA in zebrafish. We found that single morpholino knockdown of either kdr or kdrl in Tg ( fli1:EGFP; …
Zebrafish Vascular Development: General and Tissue-Specific …
2021年10月2日 · Zebrafish have 4 VEGFR-related genes: flt1(VEGFR1), kdr (VEGFR2), flt4 (VEGFR3), and kdrl (the fourth VEGFR), although mammals have 3 genes. 38 There are 3 …
Vegfa signaling promotes zebrafish intestinal vasculature development ...
2016年3月1日 · Zebrafish express two VEGFR2 homologs known as Kdrl/Flk1 and Kdr/Kdrb, and a single VEGFR3 homolog Vegfr3/Flt4 (Covassin et al., 2006). It has also been suggested that …
Evolutionary Differences in the Vegf/Vegfr Code Reveal …
2019年8月20日 · Here, we define the zebrafish Vegf/Vegfr code in receptor binding studies. We find that while Vegfd directs craniofacial lymphangiogenesis, it binds Kdr (a VEGFR2 homolog) …
The growth of endothelial-like cells in zebrafish ... - ScienceDirect
2020年7月15日 · Primary blastocyst cell cultures from transgenic zebrafish lines yield putative endothelial fli:GFP+ and kdrl:GFP+ cells. Endothelial growth supplements increase the yield of …
Targeted gene inactivation in zebrafish using engineered zinc …
2008年5月25日 · ZFNs were engineered that recognize sequences in the zebrafish ortholog of the vascular endothelial growth factor-2 receptor, kdr (also known as kdra). Co-injection of mRNAs …
Zebrafish VEGF Receptors: A Guideline to Nomenclature
2008年5月30日 · Here, we revise the nomenclature of zebrafish VEGF receptors and name the fourth vertebrate VEGF receptor gene kdr-like. The members of the VEGF family of ligands, …
Live imaging molecular changes in junctional tension upon VE
2017年11月10日 · To investigate if interfering with Vegfr2-signaling would influence maturation of the DA, we knocked down both kdr and kdrl (zebrafish Vegfr2 homologues) using morpholinos …
Evolutionary Differences in the Vegf/Vegfr Code Reveal ... - PubMed
2019年8月20日 · Here, we define the zebrafish Vegf/Vegfr code in receptor binding studies. We find that while Vegfd directs craniofacial lymphangiogenesis, it binds Kdr (a VEGFR2 homolog) …
A genetic screen for vascular mutants in zebrafish reveals dynamic ...
2009年5月15日 · Comparison of phenotypes associated with different mutations within a functional zebrafish Vegf receptor-2 ortholog (referred to as kdr-like, kdrl) revealed surprisingly …