Glial fibrillary acidic protein - Wikipedia
Glial fibrillary acidic protein (GFAP) is a protein that is encoded by the GFAP gene in humans. [5] It is a type III intermediate filament (IF) protein that is expressed by numerous cell types of the central nervous system (CNS), including astrocytes [6] and ependymal cells during development. [7]
GFAP stain - Wikipedia
In histology, the GFAP stain is done to determine whether cells contain glial fibrillary acidic protein, a protein found in glial cells. It is useful for determining whether a tumour is of glial origin.
GFAP - Overview: Glial Fibrillary Acidic Protein Immunostain, …
Glial fibrillary acidic protein (GFAP) is an intermediate filament protein of 52 kDa found in glial cells, astrocytes, and ependymal cells. Immunoperoxidase staining for GFAP produces intense cytoplasmic staining of astrocytes, glial cells, and ependymal cells in normal brain.
What is GFAP staining? - Brain Stuff
2018年9月13日 · GFAP staining is a common procedure performed in the research laboratory. GFAP itself is 52 kD. Clinically, a GFAP stain may be performed on a piece of excised brain tumor tissue to determine if the cancer is derived from glial cells.
Measurement of Glial Fibrillary Acidic Protein in Human Blood ...
1999年1月1日 · Glial fibrillary acidic protein (GFAP), found only in glial cells of the central nervous system (CNS) (1) (2), was first isolated by Eng et al. (1) in 1971. GFAP is a monomeric molecule with a molecular mass between 40 and 53 kDa (3) (4) …
Serum GFAP levels correlate with astrocyte reactivity, post …
2024年4月18日 · Glial fibrillary acidic protein (GFAP), a proxy of astrocyte reactivity, has been proposed as biomarker of Alzheimer’s disease. However, there is limited information about the correlation between blood biomarkers and post-mortem neuropathology.
A Method for 3D Immunostaining and Optical Imaging of the …
2013年8月6日 · We also evaluated 3D staining for nestin and glial fibrillary acidic protein (GFAP) (Figures 3 and 4 respectively). Nestin is a marker of neuronal stem and precursor cells in the adult mouse brain and GFAP stains both astrocytes and neural stem cells .
Glial fibrillary acidic protein (GFAP) is a 51,000 molecular weight intermediate filament protein expressed in normal, reactive and neoplastic cells (astrocytes, Bergman glis, ependymocytes and certain oligodendrocytes).
Glial Fibrillary Acidic Protein (GFAP), The Most Popular Astrocyte Marker
GFAP, a class-III intermediate filament, is a 50kDa protein which is found in the mature and developing astrocytes in the CNS, non-myelinating Schwann cells in the PNS, enteric glial cells (enteric nervous system/ENS), ependymal cells, and radial glia of the developing brain.
Glial Fibrillary Acidic Protein: The Intermediate Filament
2010年1月1日 · It is now well established that glial fibrillary acidic protein (GFAP) is the principal 8- to 9-nm intermediate filament in mature astrocytes of the central nervous system (CNS). More than 30 years ago, the value of GFAP as a prototype antigen in nervous tissue identification and as a standard marker for fundamental and applied research at an ...