Pyroptosis - Wikipedia
Pyroptosis is a highly inflammatory form of lytic programmed cell death that occurs most frequently upon infection with intracellular pathogens and is likely to form part of the antimicrobial response.
一文读懂：细胞焦亡（pyroptosis），干货满满 - 知乎
细胞焦亡（pyroptosis）是一种新的程序性细胞死亡方式，其特征为依赖于半胱天冬酶-1（caspase-1），并伴有大量促炎症因子的释放。
Cell pyroptosis in health and inflammatory diseases
2022年4月11日 · Pyroptosis plays crucial roles in host defense against infections through the release of proinflammatory cytokines and cell lysis. Accumulating evidence indicates that pyroptosis is...
Pyroptosis: host cell death and inflammation - Nature
Pyroptosis, or caspase 1-dependent cell death, is inherently inflammatory, is triggered by various pathological stimuli, such as stroke, heart attack or cancer, and is crucial for controlling...
Cell pyroptosis in health and inflammatory diseases - PMC
Pyroptosis plays crucial roles in host defense against infections through the release of proinflammatory cytokines and cell lysis. Accumulating evidence indicates that pyroptosis is associated with inflammatory diseases, such as arthritis, pneumonia, and colonitis.
Necroptosis, pyroptosis and apoptosis: an intricate game of cell …
2021年3月30日 · Pyroptosis is an inflammatory form of cell death triggered by intracellular sensors such as NLRP3 (used here as an example) that detect DAMPs, PAMPs, membrane disturbances, osmotic...
The biochemical pathways of apoptotic, necroptotic ... - Cell Press
2024年1月4日 · Apoptosis, necroptosis, pyroptosis, and ferroptosis are four forms of regulated cell death in mammalian cells that are controlled by distinctive biochemical pathways and have important physiological functions in development and immunity and pathological contributions to many human diseases including cancer, autoimmune diseases, and organ ...
Pyroptosis: Current Biology - Cell Press
2016年7月11日 · By definition, pyroptosis is a proinflammatory form of regulated cell death that relies on the enzymatic activity of inflammatory proteases that belong to the cysteine-dependent aspartate-specific protease (caspase) family.
The crosstalk between immune cells and tumor pyroptosis: …
2024年7月10日 · Pyroptosis is a cell death process characterized by cell swelling until membrane rupture and release of intracellular contents. As an effective tumor treatment strategy, inducing tumor cell pyroptosis has received widespread attention. In this process, the immune components within the tumor microenvironment play a key regulatory role.
Pyroptosis in development, inflammation and disease
2022年9月15日 · Pyroptosis is a recently discovered cell death pathway that is regulated by various microbial infections (eg, Legionella, Salmonella and Francisella) (5). Surprisingly, caspase-1, known to play a role in inflammation and cell survival, was identified as an important player in this novel cell death pathway.