Office of Cancer Clinical Proteomics Research
2024年11月20日 · The mission of the NCI’s Office of Cancer Clinical Proteomics Research (OCCPR) is to improve prevention, early detection, diagnosis, and treatment of cancer by enhancing the understanding of the molecular mechanisms of cancer, to advance proteome and proteogenome science and technology development through community resources (data and ...
Data Portal | Office of Cancer Clinical Proteomics Research
Proteomic Data Commons (PDC) represents the NCI's largest public repository of proteogenomic comprehensive tumor datasets, essentially a Proteogenomic Cancer Atlas. Proteomic data and related data files are organized into datasets by tumor type, study and sub-proteome.
CPTAC | Office of Cancer Clinical Proteomics Research
The National Cancer Institute’s Clinical Proteomic Tumor Analysis Consortium (CPTAC) is a national effort to accelerate the understanding of the molecular basis of cancer through the application of large-scale proteome and genome analysis, or proteogenomics.
Office Overview | Office of Cancer Clinical Proteomics Research
CPTAC is composed of expertise in proteomics, genomics, cancer biology, oncology and clinical chemistry, and today consists of some of the world’s largest public repositories (open community resources) of proteogenomic sequence data and targeted proteomic assays.
Computational Tools | Office of Cancer Clinical Proteomics Research
To advance precision medicine by understanding aspects of the molecular complexity of cancer, the CPTAC program develops novel approaches to process large-scale proteogenomic data sets. An important part of the CPTAC mission is to make data and tools available and accessible to the greater research community.
Milestones and Publications | Office of Cancer Clinical Proteomics …
Integrative multi-omic cancer profiling reveals DNA methylation patterns associated with therapeutic vulnerability and cell-of-origin Cancer Cell. 2023 Sep 11;41(9):1567-1585.e7. PMID: 37582362
Background | Office of Cancer Clinical Proteomics Research
The term "proteomics" refers to a large-scale comprehensive study of a specific proteome resulting from its genome, including abundances of proteins, their variations and modifications, and interacting partners and networks in order to understand cellular processes involved.
Deciphering the Tumor Microenvironment: A Proteogenomic Pan …
The study leverages proteogenomic data from samples of 1,056 treatment-naive patients with 10 different cancer types. This work is the first to report insights into cancer immunity gained from integration of comprehensive proteomics, genomic, and epigenomic data.
Proteomics in Focus: Insights from Dr. Nicole Tignor - Cancer
2024年3月20日 · The following is the third entry in a new Q&A series highlighting selected Clinical Proteomic Tumor Analysis Consortium (CPTAC) researchers and their work. Join us as we discuss multiple facets of proteomics research with Nicole Tignor, PhD, Assistant Professor at the Icahn School of Medicine at Mount Sinai. Transcript is edited for clarity.
Contact Us | Office of Cancer Clinical Proteomics Research
For more information, please contact: Office of Cancer Clinical Proteomics Research Office of the Director Division of Cancer Treatment and Diagnosis National Cancer Institute 31 Center Drive, MS 2580 Bethesda, MD 20892-2580 Phone: (240) 781-3370 Email: [email protected] For media inquiries, please contact: NCI Press Officers …