MG132, a proteasome inhibitor, enhances LDL uptake in HepG2 …
2014年7月21日 · In the current study, we employed MG132 to evaluate the potential effects of proteasome inhibition on LDL-c clearance via detection of the LDLR expression and function in …
MG132, a proteasome inhibitor, enhances LDL uptake in HepG2 ... - PubMed
Short-term treatment with MG132 (0.3 μmol/L, up to 8 h) significantly increased both LDLR mRNA and protein levels in HepG2 cells, which was blocked by the specific PKC inhibitors GF …
Inhibiting proteasomes in human HepG2 and LNCaP cells …
2000年9月16日 · Treating HepG2 cells with MG132 for 4 h to inhibit proteasomal activity increased androgen receptor immunoreactivity in two major bands with molecular weights of …
Apoptosis induced in hepatoblastoma HepG2 cells by the
This report is focused on the apoptotic effect induced by MG132, an inhibitor of 26S proteasome, in human hepatoma HepG2 cells. The results were compared with those obtained with non …
蛋白酶体抑制剂MG132促HepG2细胞凋亡及其对MDR基因表达的 …
目的:研究MG132对HepG2细胞UPP和MDR基因表达的影响,探讨MG132诱导肝癌细胞 HepG2凋亡的机制. 方法:采用流式细胞术,Hoechst33258染色,吖啶橙 (AO)染色检测HepG2细胞凋亡;采 …
蛋白酶体抑制剂MG132诱导HepG2细胞凋亡及其机制研究 - 百度 …
目的观察蛋白酶体抑制剂MG132对人肝癌细胞HepG2的致凋亡作用.并从泛素-蛋白酶体途径(UPP)相关基因E1,E2和E3及天冬氨酸特异的半胱氨酸蛋白酶3(Caspase-3)表达初步探 …
Fatty-acid-induced FABP5/HIF-1 reprograms lipid metabolism and …
2020年10月30日 · Next, we performed immunocytochemistry with MG132-treated HepG2 cells, and found that endogenous FABP5 co-exists with HIF-1α in the cytoplasm (Fig. 4f). We then …
Short-term treatment with MG132 (0.3 μmol/L, up to 8 h) significantly increased both LDLR mRNA and protein levels in HepG2 cells, which was blocked by the specific PKC inhibitors GF …
MG132, a proteasome inhibitor, enhances LDL uptake in HepG2 …
2014年7月21日 · Short-term treatment with MG132 (0.3 μmol/L, up to 8 h) significantly increased both LDLR mRNA and protein levels in HepG2 cells, which was blocked by the specific PKC …
Effects of MG132 on LDLR expression in and LDL uptake by HepG2 …
MG132, another proteasome inhibitor, can suppress PCSK9 expression in the HepG2 cells in a timedependent manner, via a SREBP-1c related mechanism.
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