Probe - National Human Genome Research Institute
2 天之前 — A probe is a single-stranded sequence of DNA or RNA used to search for its complementary sequence in a sample genome. The probe is placed into contact with the sample under conditions that allow the probe sequence to hybridize with its complementary sequence.
DNA Probes: Labeling, Types, Applications and Limitations
2019年12月20日 — DNA probes are single-stranded and labeled oligonucleotide sequences used in FISH, PCR and DNA sequencing. Learn about DNA probes, types, examples and various types of labeling techniques. Also, explore applications of DNA probes, in this article.”
DNA Probe - an overview | ScienceDirect Topics
DNA probes are single stranded (ss) or double stranded (ds), sequence specific DNA oligonucleotides (20–30 bp) designed to capture target oligonucleotides and may contain NEases recognition sites at defined positions.
Hybridization probe - Wikipedia
In molecular biology, a hybridization probe (HP) is a fragment of DNA or RNA, usually 15–10000 nucleotides long, which can be radioactively or fluorescently labeled. HPs can be used to detect the presence of nucleotide sequences in analyzed RNA or DNA that are complementary to the sequence in the probe. [ 1 ]
DNA Probe - an overview | ScienceDirect Topics
The ability to isolate specific fragments of DNA containing known sequences of genes gives rise to DNA probes that can be used for a variety of diagnostic, forensic, and therapeutic purposes. DNA probes can be labeled with either radioactive or nonradioactive markers.
DNA Probes & DNA Hybridisation | AQA A Level Biology Revision …
2021年10月26日 — When DNA probes are used in conjunction with DNA hybridisation they can indicate whether specific harmful alleles are present in a DNA sample; A DNA probe is a short length of single-stranded DNA that has a known base sequence complementary to the specific base sequence of a known allele
Isolating, Cloning, and Sequencing DNA - Molecular Biology of …
DNA probes are often used to detect, in a complex mixture of nucleic acids, only those molecules with sequences that are complementary to all or part of the probe.
DNA Probe - an overview | ScienceDirect Topics
Chromosome-specific, repetitive DNA probes, originated from the centromeric regions (alphoid DNA) and heterochromatic regions (satellite DNA), are exploited in detecting numeric alterations of the chromosomes in nondividing cells by in situ hybridization.
DNA probes - Latest research and news - Nature
DNA probes are stretches of single-stranded DNA used to detect the presence of complementary nucleic acid sequences (target sequences) by hybridization. DNA probes...
Probe Design, Production, and Applications | SpringerLink
A probe is a nucleic acid molecule (single-stranded DNA or RNA) with a strong affinity with a specific target (DNA or RNA sequence). Probe and target base sequences must be complementary to each other, but depending on conditions, they do not necessarily have to be exactly complementary.