Assessment of global health risk of antibiotic resistance genes
2022年3月23日 — Antibiotic resistance genes (ARGs) have accelerated microbial threats to human health in the last decade. Many genes can confer resistance, but evaluating the relative health risks of ARGs is...
Antibiotic resistance in the environment - Nature
2021年11月4日 — Antibiotic resistance can arise both from mutations in the pre-existing genome of a bacterium and from the uptake of foreign DNA. Mutations readily occur and become fixed in the patient or...
National Database of Antibiotic Resistant Organisms (NDARO)
To increase standardization, NCBI has developed and maintains a curated database of AMR genes and makes them available both as raw data and with an interactive web interface. To make AMR-related data more widely available, NCBI is collecting genetic and …
Antibiotic resistance genes in bacteria: Occurrence, spread, and ...
This review highlights the new mechanisms that enhance antibiotic resistance and the evolutionary background of multidrug resistance; in addition, some promising points for controlling or reducing the occurrence and spread of antimicrobial resistance are also proposed.
Forecasting the dissemination of antibiotic resistance genes …
2021年4月23日 — We use a statistical framework to identify putative horizontally transferred ARGs and the groups of bacteria that disseminate them. We identify 152 gene exchange networks containing 22,963...
Antibiotic resistance: A key microbial survival mechanism that ...
2024年6月12日 — It is built around the Antibiotic Resistance Ontology (ARO), a network that connects antibiotic resistance gene sequences and mutations to associated metadata. CARD version 3.2.9 contains 7,170 ontology terms, 5,194 reference sequences, 2,008 mutations, and 5,242 AMR detection models.
Antibiotic Resistance - StatPearls - NCBI Bookshelf
2023年6月20日 — Antibiotic resistance occurs when bacteria evolve to evade the effect of antibiotics through multiple different mechanisms. Dissemination of antibiotic resistance genes is an ecological and public health concern. Certain bacteria are able to neutralize an antibiotic by altering its component to render it ineffective.
The evolution of antibiotic resistance | Science - AAAS
2019年9月13日 — Pathogenic bacteria can acquire antibiotic resistance (ABR) genes through two main mechanisms of horizontal gene transfer (HGT): conjugation and transduction. Compensatory mutations alleviate the fitness costs imposed by ABR genes, contributing to their stabilization.
Antibiotic Resistance Mechanisms in Bacteria: Relationships …
To better understand factors that promote dissemination of resistance genes and to elucidate relationships between antibiotic resistance genes of producer, environmental, and pathogenic bacteria, new and improved strategies for sampling and screening of microbial populations and metagenomic libraries are needed.
Antibiotic resistance genes in bacteria: Occurrence, spread, and ...
2021年10月14日 — Various types of antibiotic resistance genes (ARGs) are often found in livestock manure around the world. Infections caused by antibiotic-resistant bacteria are a major threat to global public health.
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