Adenosine and Sleep: Understanding Your Sleep Drive - Sleep …
2023年12月14日 — Once you fall asleep, adenosine is believed to prolong deep sleep or slow-wave sleep. This stage of sleep plays a restorative role and allows your body to recover from …
Adenosine, caffeine, and sleep–wake regulation: state of the …
Today, adenosine is widely accepted as an endogenous sleep‐regulatory substance. In this review, we discuss the current state of the science in model organisms and humans on the …
Adenosine and Sleep - PMC - National Center for Biotechnology …
This review will briefly introduce some of the phenomenology of sleep and then summarize the effect of Ado levels on sleep, the effect of sleep on Ado levels, and recent experiments using …
The role of adenosine in the regulation of sleep - PubMed
The extracellular concentration of adenosine increases in the cortex and basal forebrain during prolonged wakefulness and decreases during the sleep recovery period. Therefore, adenosine …
Functions and mechanisms of adenosine and its receptors in sleep ...
2024年3月1日 — We demonstrate regulation function of adenosine and its receptors from arousal system, sleep-promoting system, sleep homeostasis and circadian rhythm. This article is …
Adenosine and Sleep - PubMed
The classic endogenous somnogen adenosine promotes sleep via A 1 and A 2A receptors. In this chapter, we present an overview of the current knowledge regarding the regulation of …
Regulation of sleep homeostasis mediator adenosine by basal
2020年9月4日 — Among various processes implicated in sleep homeostasis, adenosine—a critical component of the cell metabolic pathway—is a prominent physiological mediator of sleep …
Roles of Adenosine and Its Receptors in Sleep–Wake Regulation
2014年1月1日 — Adenosine, one of the potent endogenous sleep-promoting factors, accumulates in the brain during wakefulness and induces physiological sleep. Among adenosine receptors …
Sleep homeostasis: A role for adenosine in humans?
2008年6月1日 — Here we provide compelling and convergent evidence that adenosinergic neurotransmission plays a role in nonREM sleep homeostasis in humans. Specifically, a …
Physiology of Sleep - PMC
Adenosine accumulates in basal forebrain during wakefulness and diminishes with ongoing sleep . Adenosine receptors are expressed in the VLPO and adenosine activates ... There is a …