Using real time quantitative PCR, we showed that FRDA patients had residual levels of frataxin mRNA ranging between 13% and 30% and that FRDA carriers had about 40% of that of controls. Asymptomatic ...

科学家发现，转运 RNA (tRNA) 能够决定信使 RNA（mRNA）在细胞中的寿命，导致某些 mRNA 被稳定保存并翻译成更多的蛋白质，而另一些 mRNA 则被降解，从而限制蛋白质的生成量。

In this article, we are going to take a look at where Moderna, Inc. (NASDAQ:MRNA) stands against the other oversold healthcare stocks. The Promising Outlook for Healthcare Investments in 2024 ...

Given their non-migratory nature within the mineralized matrix, their unique dendrites are crucial for cell-to-cell communication in response to both intracellular and extracellular stimuli, such as ...

To create A1 lipid nanoparticles for delivering mRNA to target cells, scientists at the University of Pennsylvania used A3 coupling. A3 refers to the amine–aldehyde–alkyne coupling reaction ...

In that respect it follows a similar model to Merck's takeover of AmpTec, another CDMO that uses a PCR platform to make mRNA drugs, for an undisclosed sum last year. Outsourcing services are on of ...

CureVac and partner GSK are, meanwhile, also developing an mRNA-based flu vaccine, but are a little further back in development, as their shot is in phase 1 testing.

Type 2 diabetes (T2D) and obesity (OB) are associated with chronic low-grade inflammation and increased fracture risk. In vitro studies showed that inflammation induces bone erosion and inhibits bone ...

p < 0.05, **p < 0.01。 使用实时PCR分析，我们检测了ITGB2、MYD88、CASP1、BID、PYCARD和TNFSF10在自有LN患者队列与健康对照中的mRNA表达水平。*表示p < 0.05 ...