Ultimately, the maturation, dimerization, activation ... and colleagues showed that HSP90 inhibitors caused depletion of EGFR, the most well known ERBB, over time (Sakagami, Morrison & Welch ...

A common property of signalling receptor endocytosis is the efficient sorting ... by ligands that dissociate from them in endosomes. The EGFR agonist TGFα, for example, is released from the ...