RCT-2100 is under development for the treatment of cystic fibrosis (CF). The therapeutic candidate is an mRNA, encoding cystic fibrosis transmembrane conductance regulator (CFTR). It is administered ...

This article gives an overview of the medications for cystic fibrosis. Cystic fibrosis transmembrane conductance regulator (CFTR) modulators are a class of medications that help improve the ...

Galicaftor is under clinical development by Sionna Therapeutics and currently in Phase II for Cystic Fibrosis.

Update on evaluation of cystic fibrosis transmembrane conductance regulator modulator therapies and continued patient access (November 2023) Responding to the National Institute for Health and Care ...

Results CF neutrophils live longer due to decreased apoptosis. This was observed in both cystic fibrosis transmembrane conductance regulator (CFTR) null piglets and patients with CF, and furthermore ...

According to Vertex Pharmaceuticals, approximately 300 additional people with CF are now eligible to receive treatment.

Rage is prominently expressed in biliary epithelial cells (BECs) upon chronic cholestatic injury. Rage is a regulator of ductular reaction-mediated fibrosis. BECs release Rage-dependent Jagged1 ...

NHS England has agreed a deal with Vertex for its three-drug cystic fibrosis therapy Kaftrio, just days after the EMA’s human medicines committee recommended approval of the drug. The deal means ...

A West Kelowna woman with cystic fibrosis is taking on an important ... had threatened a classmate has been reprimanded by the regulator after they were fired by the school. According to Dec.