In human cerebral organoids, HCMV promoted Aβ and p-tau212 accumulation, suggesting that these infections could kick off AD pathology in the brain. “We think the virus contributes to AD,” Readhead ...

with greater amounts of viral proteins co-localized with tangles of phosphorylated tau -- one of the hallmarks of Alzheimer's disease pathology -- in brain regions especially vulnerable to ...

with greater amounts of viral proteins co-localized with tangles of phosphorylated tau—one of the hallmarks of Alzheimer's disease pathology—in brain regions especially vulnerable to Alzheimer ...

Iptacopan hydrochloride is under clinical development by Novartis and currently in Phase II for Granulomatosis with Polyangiitis (Wegener’s Granulomatosis). According to GlobalData, Phase II drugs for ...

NS-229 is under clinical development by Nippon Shinyaku and currently in Phase II for Granulomatosis with Polyangiitis (Wegener’s Granulomatosis). According to GlobalData, Phase II drugs for ...

Wegener’s granulomatosis (WG) is a systemic inflammatory disease whose histopathologic features often include necrosis, granuloma formation, and vasculitis of small-to-medium-sized vessels. We report ...

Wegener's granulomatosis/granulomatosis with polyangiitis is a fatal disease if left untreated, and the natural history is for only 50% of patients to survive 5 ...

Background: Follow-up data on IgA vasculitis (IgAV) in adults are scarce ... and 23 out of 191 patients without clinically apparent IgAV-associated renal pathology (12.0%) had an eGFR decline of ...

Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare form of vasculitis, meaning it causes inflammation in small and medium sized blood vessels, which can result in damage to organs ...

Wegener's granulomatosis (newly renamed granulomatosis ... with better and potentially safer treatment for the disease. The pathology of WG/GPA is characteristically described as a granulomatous ...