Cancer cells impair monocyte-mediated T-cell activation by disrupting inflammatory pathways in the tumor microenvironment.

Recent advances in immunotherapy research have revealed crucial roles for new immune cells in combating cancer, leading to ...

Prostate cancer and other cancers characterized by “cold” tumors could become more responsive to checkpoint blockade if UBA1 is inhibited.

相关成果以“多特异性嵌合体用于肿瘤免疫微环境靶向的整合免疫疗法”（Multimodal targeting chimeras enable integrated immunotherapy leveraging tumor-immune ...

University of Michigan researchers identified UBA1 as a key player in immunotherapy resistance. Inhibiting UBA1 boosts T-cell ...

A study from the University of Michigan Health Rogel Cancer Center may have—at last—cracked the cold case of immunotherapy ...

A study from the University of Michigan Health Rogel Cancer Center may have, at last, cracked the cold case of immunotherapy resistance.The research ...

MSCs hold great promise as a therapeutic tool in cancer immunotherapy due to their immunomodulatory properties, tumor-homing ...

Study uses spatial transcriptomics to map intratumoral heterogeneity and microenvironmental dynamics in triple-negative ...

In a recent article, researchers explored how calcium carbonate nanoparticles enhance T cell activation through calcium ...

Delve into the expanding and diverse field of cancer vaccines with various approaches exploiting the immune system to fight ...

Robert J. Griffin, professor of radiation biology at UAMS, will discuss possible routes to avoid or exploit tumor hypoxia for specific drug actions in cancer treatment at 12:55 p.m. Wednesday in Bell ...