Scientists uncover how disrupted lipid metabolism fuels chronic inflammation in colorectal cancer, offering insights into new ...

Keywords: Tumor microenvironment, Metabolic reprogramming, Oncometabolites, Epigenetics, Cell Metabolism, Cancer Stem Cells Important Note: All contributions to this Research Topic must be within the ...

However, it is not the tumor ... metabolism, apoptosis, senescence and differentiation. Interestingly, these processes are all sensitive to the concentration of oxygen present in the microenvironment.

The novel human cancer models comprising tumor microenvironment (TME), such as tumor organoids and organs-on-a-chip, has been established in recent years to help elucidate the underlying mechanisms of ...

Findings indicate a serine/glycine-free diet can reduce colorectal cancer growth and enhance immune response, offering ...

Chronic pancreatitis is a risk factor for the development of pancreatic cancer. Here authors report that coxsackievirus and adenovirus receptor (CAR) expression promotes pancreatitis and ...

An immuno-oncology targeting panel accurately characterized tumor-resident immune cells and located pathologically and clinically relevant tumor microenvironment features. Cancer development and ...

2The University of Texas MD Anderson Cancer Center, UTHealth Houston Graduate School of Biomedical Sciences (GSBS), Houston, Texas. 3Department of Genomic Medicine, The University of Texas MD Anderson ...