Transforming growth factor beta (TGFβ) is a cytokine that is secreted by various cell types, including macrophages, and functions in cell growth, cell differentiation, apoptosis and cellular ...

For the first time, researchers have discovered that the accumulation of aged and failing cells, called senescent cells, in ...

KROS), a clinical-stage biopharmaceutical company focused on developing and commercializing novel therapeutics to treat a ...

Surrozen (SRZN) announced a strategic research collaboration with privately-held TCGFB to discover antibody therapeutics targeting Transforming ...

TCGFB is paying Surrozen up to $6 million, plus any third-party costs, for antibodies that target transforming growth factor beta (TGF-Beta). Dysfunctional TGF-Beta is a major contributor to lung ...

This new biomaterial consists of two key elements: a bioactive peptide that binds to transforming growth factor beta-1 ...

Endothelial cells are also likely to participate in activation, both by production of cellular fibronectin and via conversion of transforming growth factor (TGF)-beta from the latent to active ...

developing a circular peptide to mimic the bioactive signal of transforming growth factor beta-1 (TGFb-1). They incorporated ...

Both STP705 and STP707 are made of two siRNA oligonucleotides that hit transforming growth factor beta 1 (TGF-β1) and cyclooxygenase 2 (COX-2) mRNA, gatekeeper targets for oncology and fibrosis.

“Major oncogenic pathways, such as mitogen-activated protein kinase, phosphoinositide 3-kinase, angiogenesis, and transforming growth factor beta, were significantly activated in CD47-high tumor ...

As a global leader in the biology of the transforming growth factor beta (TGFβ) superfamily of cell proteins and named for the visual resemblance of a scholar rock to protein structures ...