The structure of CHS complexed with resveratrol also suggests how stilbene synthase, a related enzyme, uses the same substrates and an alternate cyclization pathway to form resveratrol.

In contrast, after a 10-minute stimulation by thrombin, MLC phosphorylation levels were still elevated (163±17% compared with basal levels; mean±SEM of 3 cultures in duplicate), and MLC ...

Capital structure is the mix of debt and equity that fund a company's operations. A judicious use of debt and equity is a key indicator of a strong balance sheet. A healthy capital structure that ...

Reaction mixtures were incubated for 10 min at 33 °C with orbital shaking. Finally, 22 μl CaCl 2 (6.1 mM) were automatically added to each well with a dispenser of a Fluoroscan Ascent fluorometer ...

Background: The thrombin generation assay (TG) is a promising approach to measure the degree of anticoagulation in patients treated with direct oral anticoagulants (DOAC). A strong association with ...

Does this modest increase in phosphatidylserine significantly increase in vivo thrombin generation? Do activated monocytes provide a pathologically important surface for thrombin generation in vivo?