The genetic connections between DNA repair pathways and human cancer predisposition ... termini but cannot catalyze adenylation of the 5’-end. Thus, the 3’-OH is important for step 2 chemistry even ...
the replication checkpoint steps in and identifies the problems with the DNA. This checkpoint activates a signal transduction cascade to arrest the cell cycle and coordinate with the DNA repair ...
“So, the combination of structural data, EM data and single-molecule studies provided three powerful ... Advances in understanding DNA repair will be an important step to developing new ...
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