In its two lead cancer assets ... In 2018, researchers found TGF-β, which is elevated in the tumor microenvironment, reduces the ability of T cells to penetrate tumors, thereby reducing the ...

The so-called tumor microenvironment (TME ... has come up with a range of TME-related targets, like TGF-β, Notch, etc., supporting cancer treatment and accelerating the R&D procedure of users.

The tumor microenvironment (TME) consists of various components, including cancer cells ... each other via various cytokines including TGF-β and TNF-α, which often induce tumor progression.

Through this dual-targeting mechanism, ficerafusp alfa has the potential to exert potent anti-tumor activity by simultaneously blocking both cancer cell-intrinsic EGFR survival and proliferation, as ...

Adicet Bio, Inc. (Nasdaq: ACET), a clinical stage biotechnology company discovering and developing allogeneic gamma delta T ...

Through this dual-targeting mechanism, ficerafusp alfa has the potential to exert potent anti-tumor activity by simultaneously blocking both cancer cell-intrinsic EGFR survival and proliferation, as ...