This underscores the urgent need to analyze the immune microenvironment ... TGF-β, respectively, which are responsible for neutrophil recruitment and polarization toward N2 (Figure 1). (1) ...

The interplay between hypoxic and acidic conditions in the tumor microenvironment is unclear. Here, the authors show that hypoxic and acidic tumor cells do not fully overlap and display a ...

3- Kindlin-2 as a major regulator of the oncogenic signaling of TGF-β and cancer cell senescence: We also established Kindlin-2 as a major player in the modulation of the tumor microenvironment by ...

In 2016, cancer biologist Johanna Joyce of the Memorial Sloan Kettering Cancer Center published a study in Science that ...

Through this dual-targeting mechanism, ficerafusp alfa has the potential to exert potent anti-tumor activity by simultaneously blocking both cancer cell-intrinsic EGFR survival and proliferation, as ...

Through this dual-targeting mechanism, ficerafusp alfa has the potential to exert potent anti-tumor activity by simultaneously blocking both cancer ... TGF-β signaling within the tumor ...

A live webcast of the presentation will be available on the Events and Presentations section of Bicara’s website at www.bicara.com. An archived replay of the webcast will be available for ...

Healthy Women Have Cells That Resemble Breast Cancer Nov. 20, 2024 — A new study finds that, in healthy women, some breast cells that otherwise appear normal may contain chromosome abnormalities ...

Adicet Bio, Inc. (Nasdaq: ACET), a clinical stage biotechnology company discovering and developing allogeneic gamma delta T ...