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【JOC】酰胺化不反应,试试这种高活性的酰胺化条件,吲哚,吡唑 ...
芳香族 N-杂环(例如吲哚、吡咯、吡唑和咔唑)与羧酸直接缩合通常很难有好的收率,经常拿不到产物。主要原因是这些底物的N孤电子对会共轭到 ...
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