which will use refined inclusion/exclusion criteria and explore the benefits of earlier intervention, with separate trials for sepsis and septic shock. The ENCOURAGE trials will form the basis for ...

ARISE: 1600 patients with septic shock at 51 sites in Australia and New Zealand ProCESS: 1341 patients with septic shock at 31 U.S. sites ProMISe: 1260 patients with septic shock at 56 U.K. sites ...

Purpose. The efficacy and safety of granulocyte colony-stimulating factor (G-CSF) in critically ill patients with severe sepsis or septic shock were evaluated. Summary. The medical literature was ...

He contended that the COIITTS trial was underpowered and the two Annane RCTs that used fludrocortisone supply the evidence that shows corticosteroids reduce septic shock mortality. As discussed ...