Insertional mutagenesis as an adverse effect of retroviral gene therapy Gene therapy for SCID-X1: 5 of 20 children with leukemia correlated with upregulation of an oncogene due to nearby vector ...

It points out that all autologous CAR-Ts, like other gene therapy products, use integrating vectors like lentiviral or retroviral vectors ... which use only lentiviral vector.