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STC-15, an investigational RNA methyltransferase inhibitor, has shown promising clinical activity and an encouraging safety ...

RNA (ribonucleic acid) is a nucleic acid polymer where the carbohydrate is ribose. RNA is generally single-stranded, as DNA is transcribed by RNA polymerases into mRNA (messenger RNA), which is ...

Papers in this issue focus on original research offering novel biological and clinical insights gained using long-read DNA ...

After decades of disappointment, efforts to create jabs that can stimulate the immune system to fight cancer are showing ...

A fascinating new study, published in the Journal of Clinical Investigation, has revealed an unexpected potential benefit of ...

The genome-editing technology can be supercharged by artificial intelligence—and the results are already being felt.

This target centers on RNA regulation, which, when disrupted in humans, is often linked to neurodegenerative diseases like Alzheimer’s disease and Parkinson’s disease, as well as many types of cancer.

RNA is only one of the components that make up an mRNA vaccine. mRNA is not stable and is vulnerable to myriad RNAses ...

Mitochondrial DNA (mtDNA)-encoded RNA molecules undergo extensive processing to generate mature RNA, including removal of ...