In a paper published in Science Bulletin, a Chinese team of scientists made a significant breakthrough in major depressive ...

RNA-binding proteins (RBPs) perform diverse functions including the regulation of chromatin ... their relatively stable detection at genes encoding several neuronal and retina-disease associated ...

The RNA-binding protein FMRP regulates mitochondrial dynamics, including fusion and trafficking in neurons. A study now identifies a mechanism by which FMRP regulates mitochondrial fission.

Mechanistically, SARS-CoV-2 nucleocapsid (N) protein, which is responsible for packaging viral genomic RNA, interacts with host deaminases and co-localizes with them at stress granules to facilitate ...

A new approach for identifying new cellular RNA targets of snoRNAs uncovered thousands of previously unknown targets ...

In the wild-type virus, the Gag proteins (green ovals) bind to the PBS and ssPurines sites, leading to the encapsidation of the genomic RNA. Mutations that disrupt the long-range interaction (lower ...

Finally, it is not at all clear why a substrate binding pocket ... Nevertheless, the mechanism by which the three domains of the protein and domain IV of SRP RNA work in concert to recognize ...

Their study, published in Nature Cell Biology, shows that a protein called Serrate connects RNA modification and ... a bridge between these two crucial mechanisms. This is an important step ...

is necessary but not sufficient to enable the efficient incorporation of genomic RNA. The Gag protein is essential for the ...

ABOVE: Hematopoietic stem cells have mechanisms in place to generate intrinsically disordered proteins, which could underlie ...