The human olfactory system discriminates between thousands of odors by interacting specifically with olfactory receptors on sensory neurons. Each receptor can detect several odorants at different ...
expressing the same odor receptor converge into discrete synaptic structures of the olfactory bulb (OB) called glomeruli, forming a stereotypic odor map. The OB projection neurons, called mitral and ...
In prominent models of olfactory bulb circuitry, inhibition of mitral cells by local interneurons sharpens odor tuning and provides contrast enhancement. Mitral cell inhibition occurs at both mitral ...