The effective targeting of RAS-mutant acute myeloid leukemia (AML) still remains a challenge; RAS mutations are tied to relapse to targeted therapy, such as resistance to FLT3 inhibitors due to the ...

the disproportionate activation of the triggering receptor expressed on myeloid cells 1 (TREM-1) pathway. TREM-1 is an immune receptor expressed by myeloid and endothelial cells. Inotrem has ...

The Kharas lab is working to identify critical pathways in both normal and leukemic hematopoietic cells. MSK investigators have used a lab tool originally developed to study fly nerve cells to uncover ...

Approximately 30% of individuals with myeloid malignancy diseases have a ... 2 in Nature is the first to explain the pathway ...

University of Cincinnati Cancer Center experts will present abstracts at the 66th American Society of Hematology (ASH) Annual ...