For the first time, beta- and gamma-naphthocyclinones were successfully synthesized in a laboratory, report scientists. By combining originally developed tactics and innovative strategies, researchers ...
WNKs sense osmotic pressure by binding specific water molecules to the inactive dimeric configuration of WNK1 and WNK3, integrating signals with chloride inhibition as demonstrated by mutagenesis and ...
Department of Pharmaceutical Sciences and Computational Chemical Genomics Screening Center, School of Pharmacy, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, United States ...