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Oncology Medicinal Chemistry, Pfizer Worldwide Research and Development, 10770 Science Center Drive, La Jolla, California 92121, United States ...

Research in the fruit fly Drosophila by scientists at the University of California, Los Angeles (UCLA) has now found that buildup of a common cell structural protein, filamentous actin (F-actin ...

Buildup of a protein called filamentous actin, or F-actin, in the brain inhibits the removal of cellular wastes, including DNA, lipids, proteins and organelles. The resulting accumulation of waste ...

Actin and microtubule assembly: both mutant α-syn and LRRK2 are involved in the dynamics of actin and microtubule assembly. ER–Golgi transport: overexpression of LRRK2 may promote the improper ...