GLUCONEOGENESIS has been demonstrated in slices of renal cortex removed from rats fed on ammonium chloride, whereas rats fed on sodium bicarbonate showed a marked reduction in renal glucose ...

increased intestinal lactate production, inhibition of hepatic gluconeogenesis, decreased lipid oxidation, decreased free fatty acid concentration, and increased peripheral insulin-related glucose ...

The rules were aimed at the emerging use of continuous glucose monitors in the peloton, but the mention of lactate sparked widespread curiosity. Did the UCI’s pre-emptive ban mean that ...

Fibrosis is the outcome of any abnormal tissue repair process that results in normal tissue replacement with scar tissue, leading to persistent tissue damage and cellular injury. During the process of ...

This useful study highlights the largely redundant role of the decapping activators Edc3 and Scd6 in orchestrating post-transcriptional programs to modulate metabolic responses to nutrients in yeast.

Department of Critical Care Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China Neutrophils are essential components of the innate immune system that defend ...

2 Septic shock is defined by the need for vasopressors to maintain a mean arterial pressure over ≥65 mm Hg and a serum lactate >2 mmol/L in the absence of hypovolaemia ... in the body including ...

Abbas E. Kitabchi, PHD, MD, Guillermo E. Umpierrez, MD, Mary Beth Murphy, RN, MS, CDE, MBA, Eugene J. Barrett, MD, PHD, Robert A. Kreisberg, MD, John I. Malone, MD ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Communication of gut hormones with the central ...