Localization of cyclases and corresponding PDEs within intracellular domains, along with their varying expression across different cell types, adds multiorgan complexity to cGMP signaling. This ...

These variations are particularly evident in the intracellular domain of NKG2A, manifested as changes in mobility, tyrosine exposure, and interdomain communication. Additionally, we found that a large ...

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Notably, intracellular checkpoint molecules within NK cells, such as FBP-1, EZH2, CIS, TIPE2, and HIF-1α, play a significant role in NK cell exhaustion by affecting their metabolism ...

School of Materials Science and Engineering, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China Department of Gynaecology and Obstetrics, Shanghai Key Laboratory ...

Domain-based networks are common in companies and organization, where the process requires multiple computers to be controlled through a single node called a server. The server administrator can ...

At least 10 different types of globular protein domain are known that bind membrane phospholipids. Acidic phospholipids (especially phosphatidylserine and phosphoinositides) are the primary ...

These variations are controlled by an interplay between their intracellular transport (IT), export to the plasma membrane (PM), stabilization at synapses, and recycling. The cytosolic C-terminal ...

For one reason or the other, you may want to delete a domain user profile or account on a Windows 11/10 PC – for example, you may have a laptop that was used temporarily that you want to ...

Intracellular signalling peptides and proteins are peptides and proteins involved in transmission of signals (signal transduction) across the membrane of cells. Signals in the form of second ...

This activity requires the intracellular domain and apparently the dimerization of the transmembrane chemokine ligand. Thus, shed soluble chemokines can generate auto- or paracrine signals by binding ...