The misfolded proteins tau and α-syn cause irregular aggregation and spread in neurodegenerative illnesses, including Alzheimer’s disease (AD) and Parkinson’s disease (PD). In AD, tau protein ...
Islet endocrine cell-specific inactivation of extracellular matrix receptor integrin β1 disrupted blood vessel interactions but promoted cell-cell adhesion and the formation of larger islets. In ...
Integrin adhesion complexes (IACs) are integrin-based plasma-membrane-associated compartments where cells sense environmental cues. The physical mechanisms and molecular interactions that mediate ...