The most comprehensive map of the developing human thymus sheds light on how immune responses are built and maintained at early life, with implications for understanding and treating immunodeficiency, ...
LPX- TI641 is an oral novel Treg-expanding T cell/transmembrane, immunoglobulin, and mucin (Tim)receptor agonist therapy in development for the treatment of autoimmune diseases such as rheumatoid ...
The problem until now has been that they also suppress a part of the immune system needed to fight tumours ... One longstanding mystery has been why T cells, which are key to fighting cancer, don't ...
Bacterial superantigens (sAg) have been shown to induce T cell hyperactivation through cross linking between MHC class II on antigen presenting cells and certain TCRs on T lymphocytes. Here the ...