Antibody makeup influences the severity of flu. Viruses are the fastest-evolving biological entity on earth. This fact ...

Viruses are the fastest-evolving biological entity on Earth. This fact explains why we need flu shots every year: Seasonal ...

Chronic inflammation refers to a prolonged inflammatory response that involves a progressive change in the type of cells present at the site of inflammation. It is characterized by the ...

表达IgM-BCR和IgD-BCR的初始型B细胞负责初次抗体反应，而表达IgG-BCR的记忆性B细胞主要在抗原再次暴露时产生高滴度高亲和力的IgG型的记忆性抗体反应。

两千五百年后，现代免疫学逐渐解析了其生物学原理：病原体感染后，初始B细胞产生抗体抵御病原体，康复者获得记忆性B细胞，可快速产生IgG抗体对抗相同病原体。基于此原理，人类清除了天花病毒，有效控制了多种传染病。 近日，清华大学生命学院、CLS生命 ...

初始型B细胞主要介导初次免疫反应，而记忆B细胞则通过类别转换后的IgG-BCR在再次抗原暴露时快速应答并维持高滴度抗体反应。深入研究IgG-BCR的分子特征及ASCs中IgG抗体的稳态维持机制，对理解B细胞的免疫应答有重要意义，尤其在疫苗研发和优化免疫应答策略 ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. ADAM12, a disintegrin and metalloprotease, is ...

Drugs that specifically inhibit BCR signaling elements are currently being tested in clinical trials. The promising results obtained so far suggest that in the near future we may have novel ...