The FDA has approved imatinib oral solution (Imkeldi) for the treatment of certain forms of leukemia and other cancers. This is the first oral liquid form of imatinib for the treatment of select ...

The 3.0 utilizes the same basic concept, but adds a pressure boosting mechanism and an energy recovery system. As a result, it's said to be easier to pump than the original and faster at ...

Antiangiogenic therapy (AAT) aims to normalize tumor blood vessels by inhibiting these angiogenic signals. In this review, we will explore the molecular mechanisms of angiogenesis within the tumor ...

For most of the 20th century, doctors treated cancer by hitting it with everything they had. Radical surgery, high-dose radiation, brutal chemotherapy. Even when it worked, the collateral damage ...

Deputy Finance Minister Lim Hui Ying assured the public that Putrajaya has the right mechanisms in place to ensure that the local currency doesn’t slide further. Lim said the government was ...

The tyrosine kinase inhibitor imatinib targets the human KIT receptor ... Major insights into the mechanism of action of this drug, drug resistance, and patient management issues have been gleaned.

Chronic myeloid leukaemia (CML) blockbuster Gleevec has been badly hit by generic competition in the US, revenues falling 30% to $834 million in the period. This decline will continue, with ...

Langmuir identified CO oxidation (gaseous CO colliding with O* atoms) over Pt catalyst as an example of a reaction occurring via this mechanism. (3) Noting the differences between gas-phase, ...

Thus, several potential systemic treatment options currently exist for patients whose tumors progress during imatinib treatment. Based on the insights into the mechanisms underlying sensitivity to ...

State Key Joint Laboratory of Environmental Simulation and Pollution Control, State Environmental Protection Key Laboratory of Atmospheric Ozone Pollution Control, College of Environmental Sciences ...