Figure 1: Delivery of synthetic shRNA into Nanog-GFP mouse ES cells. M15 ES cell medium with leukemia inhibitory factor (LIF): DMEM Knockout (Gibco), 15% fetal bovine serum (FBS; StemCell ...

Endocannabinoids, molecules naturally produced in the brain, play a critical role in regulating appetite, energy use, and ...

Researchers at Baylor College of Medicine, Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas ...

With Gene Editing, Mice With a Form of Inherited Deafness Can Hear Again July 12, 2024 — Researchers have used gene editing to restore hearing in adult mice with a type of inherited hearing loss.

This study investigates the role of Aff3ir-ORF2, a novel nested gene variant, in disturbed flow-induced endothelial cell activation and atherosclerosis. We demonstrate that disturbed shear stress ...

Scientists explore how daily glucocorticoid signaling influences glioblastoma growth and synchronizes its circadian rhythms ...

Experiments in mouse models showed the gene therapy strategy significantly reduced the tumor burden compared to untreated animals in two fast-growing, difficult-to-treat cancers: glioblastoma ...

Researchers have uncovered how loss of the MeCP2 protein triggers early molecular changes leading to Rett syndrome, a severe ...

A previously unknown population of neurons in the hypothalamus may pave the way for new obesity treatments. Obesity impacts a ...

This fundamental study substantially advances our understanding of the role of zinc in metabolism, specifically a newly established clinical link between mutations in the zinc transporter SLC39A5, ...

Antimicrobial peptides derived from a crab and a spider may provide the pathway to overcoming drug resistance in advanced melanoma.